How can I tell early on that my goat has hypocalcemia?
Ask yourself: In the early months of pregnancy (or during lactation, if
she is in milk) have I been feeding my doe a regular, ample grain ration
along with her hay? And especially, have I been feeding this ample grain
ration along with grass hay instead of alfalfa?
Signs to watch for any time from the 12th week of
the pregnancy on:
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Does the doe gradually or suddenly lose interest in her grain ration?
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And soon after that, does she also lose interest in her hay ration?
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If this is the case, and if no corrective action is taken quickly, you
can expect the next signs to be: She weakens fast, acts lethargic, is
depressed. Her rear legs appear wobbly. If this situation is allowed to
progress without intervention, she goes down and won't get up. Her body
temperature will be normal (102.3) when these signs first appear, but
will drop to sub-normal (below 102) as they progress. These symptoms are
classic for hypocalcemia. Without fast and correct intervention she will
die.
What is hypocalcemia?
Hypocalcemia (calcium deficiency) is a serious condition in which the
calcium that a doe needs to support herself and provide for the needs of
her developing fetuses (or to produce milk if she is lactating) is
unavailable to her because of incorrect feeding.
What steps can I take to correct this?
(Before continuing, I want to point out that any dosages I mention
herein are intended for full-sized dairy-type does, weighing ~ 120-150
lbs avg. If the doe your are concerned about is of a smaller variety you
will need to adjust recommended doses accordingly.)
Immediately, and time is of the essence here, start her on Nutridrench
or oral propylene glycol to provide her with the necessary energy so
that she will not become ketotic. (Ketosis is a metabolic problem caused
by the animal's having to live on its own body reserves because it has
stopped eating food. If not corrected, this will result in coma and
subsequent death.). I recommend either the appropriate dose of
Nutridrench for her weight, or 60cc propylene glycol, 2x daily for 2
days to restore her, with 30cc daily thereafter until she is clearly
eating properly again, to prevent/reverse ketosis.
Then, start her on calcium replacement therapy quickly. While calcium
gluconate is commonly used for this, I prefer a product called CMPK (or
a generic substitute thereof), because calcium gluconate contains only
calcium, whereas the CMPK products contain magnesium, phosphorus, and
potassium as well, all of which make the calcium more readily available
for the body to use. Logic tells us that calcium that is in combination
with these other elements that make it work better will be able to
correct the deficiency and restore the doe to health much faster than
can a product that contains the same amount of calcium alone, with no
enhancements. One caveat: keep in mind that a single dose, or only a few
doses, of this product will ONLY balance the doe's calcium level FOR THE
MOMENT, but those babies will continue to grow and to drain her system
of the needed calcium and phosphorus, so you will need to continue the
doses daily until she freshens and is eating sufficient amounts of
properly balanced nutrients to enable her to lactate properly.
The CMPK should be given at the rate of 30cc (1oz) every 2 hours or so
until she appears bright and alert and willing to eat once more. The
reason we give this specific amount every two hours, instead of giving a
larger dose less often, is because calcium, necessary for muscle
contractions, plays a vital role in the proper beating of the heart. But
the downside of that is that to give a larger dose all at once,
particularly at the later stages of the treatment, might actually cause
the heart to beat too rapidly and create further difficulties to add to
the ones the doe is already experiencing. We avoid this potential for
overdose by giving smaller amounts more often, as I
recommend here. I advise people who are administering calcium to check
its effect upon the patient's heart by periodically checking the heart
rate of another, normal doe (70 - 80 beats per minute), and comparing it
with that of your hypocalcemic doe. Initially the hypocalcemic doe's
heart rate will be considerably slower than that of the normal doe
because she lacks the calcium to keep it beating normally. When the
treated doe's heart rate is the same as, or a tiny bit faster than, the
normal doe's heart rate, things are going well.
After bringing her heart rate up to normal, she will need DAILY
MAINTENANCE DOSES OF ~ 30cc (1oz), continuing UNTIL SHE FRESHENS, at
which point she will no longer need to provide large amounts of calcium
and other nutrients for the fast-growing fetuses within her. Should she
start to deteriorate at any time before then, that amount should be
increased appropriately, but oonly temporarily, until she is regulated
once more. Hopefully, for future pregnancies this doe's diet will be
corrected so that this disorder will not re-occur.
BTW: Once her calcium level has been regulated and she resumes eating,
she will probably initially refuse any grain that is offered. That
should not cause you concern because her instinct is still trying to
regulate her calcium-deficient condition and she is the best monitor of
that. In short order she will probably resume eating the grain again, at
which time she should be limited to just a small amount at each feeding.
If she is not eager at first to eat her hay (grass is OK initially if
that's what you have access to... Alfalfa or alfalfa pellets would be a
really good choice now) you would be wise to bring her some of her
favorite browse... I feed Salal up here in the Northwest, and the wild
huckleberry, both of which stay green all winter... In your area there
must be something yummy that, of
course, is not toxic. If you don't know her favorite, give her a variety
and let her choose.
If possible, it would be better to use injectable CMPK instead of the
oral form to treat your doe. This is because: (a) It's always risky to
dose a seriously debilitated animal orally as there is a potential for
part of the fluids to end up in the lungs of the struggling animal,
resulting in
aspiration pneumonia, and (b) Calcium is, in concentrated form, somewhat
caustic, and it will often burn the tender membranes of your goat's
throat. The problem with my telling you this is that in their infinite
wisdom the powers that be have decreed that injectable CMPK, while
relatively inexpensive (about $4/1000ml in the catalogs) should be a
prescription-only item, available therefore only under the guidance of a
veterinarian. The down side of this is that in addition to an increased
per-dose cost, many veterinarians, especially those that are not
goat-oriented, may not understand hypocalcemia, or why continued doses
are necessary. As a result
they might be overly-cautious about its use and generally will only want
to prescribe/provide a single dose, or perhaps two. This is tantamount
to trying to fix a leaking dam by putting your finger in the hole to
stop the water flow.
One additional, important note regarding treatment of your hypocalcemic
doe:
While you are treating her, keep in mind that if this very weak and
debilitated doe has been down for 3 or more days, it is essential that
you get her back up on her feet ASAP. Otherwise her legs will quickly
lose their muscle tone and be unable to support the heavy weight of her
body if she tries to get up on her own. If she is allowed to remain down
for too long a period, her leg joints may begin to 'ankylose', or freeze
permanently in the bent position. This is irreversible. To prevent it
you may have to create a makeshift 'sling', attaching it to a pulley
that is fastened to an overhead beam in the barn. About every 2 hours
the sling should be raised up so that she can touch the ground
comfortably with her feet and move around, and then lowered again so she
can rest for a while... The process should be repeated continuously, 2
hours up and 2 hours down,
until she can once again support her body's weight with her own legs.
This generally takes but a few days, though her pregnant condition may
place an added burden upon her as she tries to get her strength back. If
the reader wants a picture of a sling I have one in my archives, at sreith@qwest.net..
How could my pregnant goat get hypocalcemia? And how can I prevent
it?
If your doe is still milking when she is bred, she will need to continue
the ration you have been giving her to support her milk production. But
if she is 'dry' (not lactating) when you breed her she will need little
or no grain for the first 3 months of her pregnancy, as calcium is not
yet required for support of fetal growth. You see, at 3 months the fetus
is no bigger than a newborn baby kitten.
But once that first 90 days or so has passed, the now completely formed
fetus starts to grow rapidly. It will continue to do so, making
increasingly greater demands for calcium to achieve that, over the next
8 weeks. So it's appropriate at that point to begin giving a small
amount of
alfalfa with the grass hay, increasing it gradually until at the time of
freshening she is getting all alfalfa, which in my view should be
continued for the length of time she remains in milk. The feeding of
alfalfa should taper off only as her milk production tapers off, until
she reaches the end of that lactation, at which time she can once again
be given all grass hay.
At that same 90 day (3-month) point when you start giving the pregnant
doe alfalfa, you should also start offering a small amount of grain, no
more than a handful at a feeding. It should be increased slowly over the
next 60 days (2 months) so that by the time the animal freshens she is
getting maybe a cup in the morning and a cup at night. Then, depending
on the amount of milk the doe is giving per milking, you should increase
the grain so that she is getting enough to help produce the milk but not
make her fat. A pound of grain is usually recommended for 8 lbs (~ a
gallon) of milk. I add alfalfa pellets to a doe's grain to keep her busy
while I milk her out.
The cause of this hypocalcemia (calcium deficiency) problem that can
show up in a doe anytime in the last 6-8 weeks of pregnancy is very
basic. How best to explain it? Let's see... Most of us know that water
is made up of a ratio of 2 parts Hydrogen to 1 part oxygen (H2:0). If
you don't have that ratio, you don't have water. And some of us,
particularly those among us that are raising goats in copper-deficient
areas, understand that a ratio of 10 parts copper to 1 part molybdenum
(10:1) is essential in order for copper to be available for our goats.
Following that line of thinking, a ratio of 2 parts calcium to 1 part
phosphorus (2:1) is needed to make calcium available to us, AND to our
pregnant/lactating goats. If we don't have 2 parts of calcium for every
1 part of phosphorus, calcium isn't available. So you can see now how
important it is that all of these ratios remain in balance. When they
are not, the substance we need will not be available to us. In line with
this, the goat must be provided with a ratio of at least 2 parts calcium
(abundant in alfalfa) to 1 part phosphorus (abundant in grain) to make
the calcium available to her that she must have to support herself as
well as the rapid fetal development within her uterus (or a lactating
udder). If her owners do not provide the correct balance for her in the
feed she is given, she will become hypocalcemic (calcium-deficient).
At the beginning of the gestation, before the babies start demanding a
lot of calcium so they can grow within her, a mature doe (not a
yearling, however, that is herself still growing) can survive on an
unbalanced diet heavy in phosphorus (in grain) and virtually devoid in
calcium (in alfalfa),
generally without serious consequences. But when suddenly at 3 months
into her gestation her body starts needing lots of calcium for the
babies' growth, with that same unbalanced diet she's been getting all
along the calcium will not be available! Even if she were getting lots
of good alfalfa along with that ample grain ration, she simply would not
have the rumen capacity to eat enough alfalfa to achieve the 2:1 balance
necessary to release sufficient calcium to meet the demands of her own
body AND the rapidly growing fetuses inside of her. Her amazing instinct
tells her to cut back on the grain to free up calcium from the hay.
Well, when she stops eating
that large amount of high-energy grain she has become accustomed to, she
quickly becomes nutritionally deprived, in addition to the calcium
deficiency she is already experiencing. She weakens fast, becomes
lethargic and wobbly, and goes down, and owners and consulting vets
stand around scratching their heads, not realizing what led up to this,
and try to figure out what's wrong. They (might) offer her Nutridrench
or propylene glycol to correct the ketotic situation she finds herself
headed for (or in), and then they wonder why she continues to get weaker
and weaker, not realizing her problem is that the mismanagement of her
feeding program has deprived her of much needed calcium, vital not only
for the babies' development, but for her own muscle tone as well. No
calcium, no muscle tone, no heart pumping, dead goat.
I can't find anything in the goat books about this disease. Where can
I get more information?
Hypocalcemia is a correctable metabolic disorder (condition), and not
a disease. Regarding the lack of resource material covering this
disorder, I will say that I have been making a valiant effort to
encourage the veterinarians who write these books to update their work
to include it, but progress is slow. While most of goat management
coverage in our current resource books is quite helpful, in this
particular area I see the following deficiencies:
In the Merck Veterinary Manual a single sentence does address
this disorder that appears at times in later gestation. In the 8th
Edition it is found on P.744, the 'Pregnancy Toxemia in Ewes' section,
in the paragraph called 'Diagnosis'. The single sentence reads:
"Hypocalcemia, uncomplicated by pregnancy toxemia, should always be
considered for recumbent late-gestation
sheep." That's it! There is no discussion of either causation or
treatment to be found anywhere for this briefly referred-to
hypocalcemia. I can only speculate that it is because it is not well
understood by the author.
Smith and Sherman's 'Goat Medicine' book does a fine job of pointing out
in the section on goats' dietary needs that a diet containing 2 parts
calcium for every 1 part phosphorus is important. Unfortunately, it
appears there was a lapse in transferring that information over into
other areas of the book where it is needed. For example, in a discussion
of 'metabolic disorders appearing in late gestation' a reference is made
to hypocalcemia, which is then followed up by a vague comment about some
magical but unexplained chemical imbalance within the hypocalcemic goat
that makes calcium unavailable to her. The author fails to make use of
this golden opportunity to explain to the reader (many of whom do not
understand the nutritional needs of a pregnant/ lactating goat) the
importance of providing a diet that contains 2 parts calcium for every 1
part phosphorus to free up calcium for her fetuses/milk production in
order to prevent this hypocalcemia . Once again, I am left to assume
that the authors are not making this connection? Oddly, there is another
comment in that same section on metabolic disorders about goats needing
"2 parts 'forage' to 1 part 'concentrate'", a misleading
statement at best, and a recipe for disaster at
worst, since vast numbers of goat owners have only grass for forage, and
grass contains very little calcium at all.
John Matthews, in his 'Diseases of the Goat', talks about
'hypocalcaemia', noting that it may appear in late pregnancy... AND in
any stage of lactation (an important bit of information!). Sadly, he
also misses the simple cause, a dietary imbalance that prevents the
uptake of calcium from the feed, and relies on that magical but
unexplained "failure in the homeostatic mechanisms to meet the
increased demand for calcium". However, in his discussion of
'Hypocalcaemia' he does redeem himself admirably with the accuracy of
the following statement that: "All recumbant or comatose goats
should be treated as potentially hypocalcaemic and given calcium."
Disappointingly, in addition to failing to explain the actual cause of
hypocalcemia (unbalanced diet), none of these popular reference books
offer any suggestion that continued calcium replacement during this
owner-created crisis be started as a treatment for it. In fact, all
excepting John Matthews' book actually make very little of hypocalcemia,
despite the fact that (while admittedly it remains unrecognized due to
lack of text reference information on the subject) it shows up quite
frequently in the 'down' pregnant/lactating does managed by
inexperienced goat owners. As a result, its potential for use as a
diagnosis is overlooked entirely by veterinarians
seeking guidance from these books in their efforts to come up with a
proper diagnosis and treatment for the animal. The huge down side of
this is that when the hypocalcemic condition is not recognized, the
veterinarian that is inexperienced in diagnosing 'down' pregnant goats
will, using these books for reference, almost always opt for a diagnosis
of Pregnancy Toxemia, or
Pregnancy Ketosis, or any combination or variation of those words. When
asked directly about the possibility of a calcium deficiency, he/she
frequently responds, "This goat's problem has nothing to do with
calcium." The predictable treatment regimen will then be:
"Treat with propylene glycol for ketosis, and get the babies out
fast (C-section or, even worse, suggestion of Lutalyse for abortion,
which will not work because the uterus has no muscle tone with which to
expel the fetuses when put into the labor mode) to save the life of the
doe." In instituting calcium therapy in lieu of such drastic
measures I have never experienced loss of either the doe or the
kids, and does thus properly treated to correct the condition invariably
go on to freshen normally. Were it my goat down with this problem I
would most surely engage the vet as a partner in instituting this
treatment prior to embarking on anything so drastic as C-section or
abortion!
A number of our foremost dairy goat nutritionists and veterinarians have
made reference to the existence of hypocalcemia in their writings over
the years, although none seem to address the actual cause of it, which
is critical to its treatment. As actual livestock management is not
their field, perhaps they assume that all dairy goat people
instinctively understand how to correctly feed their pregnant stock?
They apparently are unaware that it is the mistakes in the feeding
programs made by those of us who do not understand this essential 2:1
nutritional need that cause this hypocalcemic (too little calcium)
condition.
Here are a couple of contributions made by respected individuals that
have helped us in our understanding of goats' dietary needs, and have
suggested potential corrective measures to take when the needs are not
met:
Dr M.E. Ensminger, a renowned livestock nutritionist from whose work a
vast body of our experts draw today in order to determine the content of
livestock feeds and make nutrition recommendations, says in his 'bible'
of livestock nutrition called Feeds & Nutrition - Complete,
published in 1978, that Alfalfa (lucerne), a legume, "is high in
calcium, protein, and carotene, and in many other minerals and
vitamins". He notes that "legumes are excellent calcium
sources, while grasses and silages tend to be substantially lower in
calcium content". He points out clearly that both bone growth and
lactation (and muscle tone as well, BTW) require substantial
quantities of these minerals. He says, "If there is a severe
imbalance of them during pregnancy and early lactation, 'milk fever'
<smile> may occur." And he continues, "Therefore, in
order to prevent these problems, the calcium:phosphorus ratio should be
at least 2:1." (2 parts calcium: 1 part phosphorus.) (FYI: He also
states: "In males an imbalance of calcium to phosphorus often leads
to the development of urinary calculi.")... Finally, as an addendum
to those among us who rely on grass hay to feed our goats, Dr Ensminger
suggests that where additional calcium is needed, ground limestone is
generally the mineral of choice, but if the animals are in need of both
calcium and phosphorus the best choices for provision of these 2
essential minerals are di-calcium phosphate or steamed bone meal.
Another knowledgeable person, a man with whom I had the good fortune to
come into contact when I was living in So. California where I first
began to raise dairy goats, was a veterinarian named Dr Robert A.
Jackson. He was what you could call a goat vet's goat vet, and he and a
dairy goat breeder/judge named Alice Gaye Hall frequently co-wrote
articles on dairy goat management. In one such article, printed in the
July '82 Dairy Goat Guide and entitled 'What to Know about Medications',
the readers were advised that calcium is an important substance for goat
owners to keep in their cupboards because goats often come down with 'eclampsia,
which is much like milk fever...'. As do others, they called it milk
fever when it is actually just one of the elements one finds in that
disease, and while they don't address its dynamics, they do make the
observation that a calcium deficiency (hypocalcemia) sometimes exists in
the pregnant/lactating goat, and that the owner should be prepared to
treat it when it shows up.
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